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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
9.7
Human Site:
S638
Identified Species:
16.41
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S638
S
P
P
Q
P
I
L
S
R
G
R
P
D
S
N
Chimpanzee
Pan troglodytes
XP_509441
819
90122
K608
P
Q
N
N
C
S
G
K
S
D
P
K
N
V
A
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
L201
K
S
S
R
E
E
D
L
L
A
P
K
Q
A
E
Dog
Lupus familis
XP_546925
857
93734
S643
S
P
P
Q
P
I
L
S
R
G
R
P
D
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S650
S
P
P
Q
T
V
L
S
R
G
R
V
D
N
N
Rat
Rattus norvegicus
Q6AXT8
471
49872
P282
P
G
P
P
Q
M
P
P
P
A
P
G
V
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
R682
S
L
H
H
P
P
S
R
R
G
R
P
D
S
S
Frog
Xenopus laevis
NP_001084764
548
60887
P359
L
I
P
S
P
G
P
P
A
I
V
P
V
R
E
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
S613
P
Q
S
P
L
S
T
S
T
G
M
S
K
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
T617
Q
D
S
P
L
S
P
T
T
S
L
K
F
Q
P
Honey Bee
Apis mellifera
XP_394429
1014
115124
K799
S
P
N
R
G
Y
I
K
G
E
T
E
R
G
Q
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
A700
S
G
D
I
S
G
P
A
S
V
P
V
Q
A
S
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
F1100
T
S
S
L
A
S
V
F
T
S
P
Q
S
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
D870
S
E
A
S
K
A
P
D
I
D
M
T
E
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
0
0
93.3
N.A.
73.3
6.6
N.A.
N.A.
53.3
20
13.3
N.A.
0
13.3
6.6
13.3
P-Site Similarity:
100
6.6
13.3
100
N.A.
86.6
13.3
N.A.
N.A.
60
20
20
N.A.
6.6
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
8
8
15
0
0
0
15
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
8
8
0
15
0
0
29
0
0
% D
% Glu:
0
8
0
0
8
8
0
0
0
8
0
8
8
0
29
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
15
0
0
8
15
8
0
8
36
0
8
0
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
8
0
15
8
0
8
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
15
0
0
0
22
8
0
0
% K
% Leu:
8
8
0
8
15
0
22
8
8
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
0
15
8
0
0
0
0
0
0
0
0
8
22
29
% N
% Pro:
22
29
36
22
29
8
36
15
8
0
36
29
0
0
15
% P
% Gln:
8
15
0
22
8
0
0
0
0
0
0
8
15
8
8
% Q
% Arg:
0
0
0
15
0
0
0
8
29
0
29
0
8
8
0
% R
% Ser:
50
15
29
15
8
29
8
29
15
15
0
8
8
22
15
% S
% Thr:
8
0
0
0
8
0
8
8
22
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
8
8
15
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _